Composition:
Each uncaoted tablet contains:
Rosuvastatin Calcium IP
Eq. to Rosuvastatin 10 mg
Each film coated tablet contains:
Rosuvastatin Calcium
Eq. to Rosuvastatin 20 mg
Mechanism:
Statins are 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors that are effective in the reduction of total and LDL cholesterol.3 A number of large randomized control trials have demonstrated unequivocally that lowering LDL-C particularly with statins reduces the risk of cardiovascular deaths and events.4 HMG CoA inhibitors have been shown to prevent initial cardiovascular events and subsequent cardiovascular events in ischaemic heart disease patients, irrespective of the cholesterol concentration.5,6 In addition to the beneficial cholesterol lowering effects, statins improve endothelial function, enhance stability of atherosclerotic plaques, and inhibit inflammatory as well as thrombogenic responses in arterial walls.
Indication:
As an adjunct to diet in the treatment of triglyceridemia, Primary Dysbetalipoproteinemia (Type III Hyperlipoproteinemia), and Homozygous Familial Hypercholesterolemia.
Dosage:
One tab once daily or to be taken in a dose and duration as directed by the Physician.
